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14 Nov 2024
6 min read
5
0
The lab partner you can count on: Multitron incubator shaker

In the fast-paced world of bioprocessing, having reliable lab equipment is critical for research and process development success. The Multitron incubator shaker has been designed with these demands in mind, offering precision and efficiency that directly address the challenges scientists face in their labs. Whether you are optimizing culture conditions or scaling up processes, the Multitron shaker provides the tools you need to advance your research with confidence.

14 Nov 20246 min read50
The lab partner you can count on: Multitron incubator shaker

In the fast-paced world of bioprocessing, having reliable lab equipment is critical for research and process development success. The Multitron incubator shaker has been designed with these demands in mind, offering precision and efficiency that directly address the challenges scientists face in their labs. Whether you are optimizing culture conditions or scaling up processes, the Multitron shaker provides the tools you need to advance your research with confidence.

23 Oct 20249 min read40
Optimizing HEK293 cell cultures for gene therapy applications: the role of incubator flexibility

Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.

16 Oct 20248 min read12
The 7 "deadly sins" of shake flask culture

Simple actions can make a lot of difference to the outcome of your shake flasks cultures. Some beneficial ones have been covered in previous articles, however, common practices can also be a barrier to effective optimization. This article will explain why these common practices count as sins against your shake flask culture and what you can do to overcome them. 

20 Sep 20244 min read50
Sustainable dairy innovation: Daisy Lab uses precision fermentation to produce animal-free milk proteins in INFORS HT bioreactors

As demand for sustainable food sources surges, Daisy Lab is revolutionizing dairy production with precision fermentation technology. By using INFORS HT bioreactors, this New Zealand-based startup is producing animal-free milk proteins like whey and casein. Discover how the innovative process at Daisy Labs, now set to scale with EPA approval, is paving the way for a more sustainable future in dairy.

05 Sep 20246 min read0
How clean is your incubator shaker?

Cleaning an incubator shaker sounds trivial, but it is critical for cultivation success. The good news is that doing the right thing is simple, effective, and can easily be integrated into the routine management of a laboratory.

30 Aug 202410 min read0
Single cell protein (SCP) production from industrial by-products using repeated fed-batch
A cross-interdisciplinary collaboration is increasing the sustainable value creation in Norwegian aquaculture and agriculture by using industrial by-products as a nutrient source for yeast-based Single Cell Protein (SCP). The microbial ingredient is used as a high-value locally produced protein source in animal feed with health-promoting components. But how to meet the demand for more biomass? The success story of the Norwegian University of Life Sciences (NMBU) shows us a way to increase production capacity.

 
24 Jun 20244 min read52
Transforming bioprocess research and development with INFORS HT bioreactor system design

Discover how INFORS HT’s bioreactor systems enhance bioprocess R&D for the Agro-Biotechnology Institute. Explore their streamlined operations and optimized yields. An interview-style article with Dr. Siti Rokhiyah PhD., Head of Bioreactor Unit at the Agro-Biotechnology Institute (ABI), National Institutes of Biotechnology Malaysia (NIBM) in Malaysia.

17 Jun 20244 min read4,50
From classrooms to pilot production: leveraging INFORS HT innovations for bioprocess scale-up

Discover how INFORS HT bioreactors and services have supported bioprocess education and research at Universiti Sains Malaysia (USM). Joo Shun TAN (陈裕声), Associate Professor, shares insights on leveraging Minifors, Multifors, and Techfors bioreactors to enhance teaching, research, and scale-up processes.

17 Apr 20243 min read40
Biotech company uses microbial fermentation process in carbon recycling technology

Zara Summers, Chief Science Officer at LanzaTech, a Biotech Company, vividly articulates the company goal to reduce fossil fuel consumption and instead, recycle carbon, that is already above ground to create necessities: "We want it so every child in the world can pick up a crayon and color the sky and have that crayon that they pick be blue. Right? And today that is not the reality for every kid around the world."

13 Apr 20244 min read4,30
Enhancing plasmid DNA (pDNA) production: Innovations in process, manufacturing, and purification techniques

A plasmid DNA production process was performed comparing conventional Erlenmeyer flasks with LB medium and the Thomson’s Ultra Yield® system. E. coli cells were cultivated in both systems in the INFORS HT Multitron incubator shaker, bacterial growth was monitored, and the plasmids were purified at the end of cultivation. Subsequently, the quality of the isolated plasmids was analyzed by HPLC. The combination of the Ultra Yield® flasks with the enriched Plasmid+® medium and the AirOtop® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.

23 Oct 20249 min read40
Optimizing HEK293 cell cultures for gene therapy applications: the role of incubator flexibility

Gene therapy is a promising approach for treating various genetic disorders and diseases. A critical component of gene therapy is the production of viral vectors, which serve as delivery vehicles for therapeutic genes. Human Embryonic Kidney 293 (HEK293) cells have become a widely used platform for viral vector production due to their efficiency in transfection and ability to support viral replication. However, optimizing HEK293 cell cultures for large-scale production of viral vectors remains a challenge in making gene therapies more accessible and cost-effective.

16 Oct 20248 min read12
The 7 "deadly sins" of shake flask culture

Simple actions can make a lot of difference to the outcome of your shake flasks cultures. Some beneficial ones have been covered in previous articles, however, common practices can also be a barrier to effective optimization. This article will explain why these common practices count as sins against your shake flask culture and what you can do to overcome them. 

20 Sep 20244 min read50
Sustainable dairy innovation: Daisy Lab uses precision fermentation to produce animal-free milk proteins in INFORS HT bioreactors

As demand for sustainable food sources surges, Daisy Lab is revolutionizing dairy production with precision fermentation technology. By using INFORS HT bioreactors, this New Zealand-based startup is producing animal-free milk proteins like whey and casein. Discover how the innovative process at Daisy Labs, now set to scale with EPA approval, is paving the way for a more sustainable future in dairy.

05 Sep 20246 min read0
How clean is your incubator shaker?

Cleaning an incubator shaker sounds trivial, but it is critical for cultivation success. The good news is that doing the right thing is simple, effective, and can easily be integrated into the routine management of a laboratory.

30 Aug 202410 min read0
Single cell protein (SCP) production from industrial by-products using repeated fed-batch
A cross-interdisciplinary collaboration is increasing the sustainable value creation in Norwegian aquaculture and agriculture by using industrial by-products as a nutrient source for yeast-based Single Cell Protein (SCP). The microbial ingredient is used as a high-value locally produced protein source in animal feed with health-promoting components. But how to meet the demand for more biomass? The success story of the Norwegian University of Life Sciences (NMBU) shows us a way to increase production capacity.

 
24 Jun 20244 min read52
Transforming bioprocess research and development with INFORS HT bioreactor system design

Discover how INFORS HT’s bioreactor systems enhance bioprocess R&D for the Agro-Biotechnology Institute. Explore their streamlined operations and optimized yields. An interview-style article with Dr. Siti Rokhiyah PhD., Head of Bioreactor Unit at the Agro-Biotechnology Institute (ABI), National Institutes of Biotechnology Malaysia (NIBM) in Malaysia.

17 Jun 20244 min read4,50
From classrooms to pilot production: leveraging INFORS HT innovations for bioprocess scale-up

Discover how INFORS HT bioreactors and services have supported bioprocess education and research at Universiti Sains Malaysia (USM). Joo Shun TAN (陈裕声), Associate Professor, shares insights on leveraging Minifors, Multifors, and Techfors bioreactors to enhance teaching, research, and scale-up processes.

17 Apr 20243 min read40
Biotech company uses microbial fermentation process in carbon recycling technology

Zara Summers, Chief Science Officer at LanzaTech, a Biotech Company, vividly articulates the company goal to reduce fossil fuel consumption and instead, recycle carbon, that is already above ground to create necessities: "We want it so every child in the world can pick up a crayon and color the sky and have that crayon that they pick be blue. Right? And today that is not the reality for every kid around the world."

13 Apr 20244 min read4,30
Enhancing plasmid DNA (pDNA) production: Innovations in process, manufacturing, and purification techniques

A plasmid DNA production process was performed comparing conventional Erlenmeyer flasks with LB medium and the Thomson’s Ultra Yield® system. E. coli cells were cultivated in both systems in the INFORS HT Multitron incubator shaker, bacterial growth was monitored, and the plasmids were purified at the end of cultivation. Subsequently, the quality of the isolated plasmids was analyzed by HPLC. The combination of the Ultra Yield® flasks with the enriched Plasmid+® medium and the AirOtop® enhanced seal led to higher cell densities and a 21-fold higher amount of plasmid than in Erlenmeyer shake flasks with LB medium.

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